BDBM50493647 CHEMBL2437436

SMILES OC(=O)C(F)(F)F.[H][C@]1(C[C@H]1c1cccc(CCc2ccccc2)c1)[C@]1(C)CC(=O)N(C)C(N)=N1

InChI Key InChIKey=YRTXMTMVCLFETE-JOEGFDNXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50493647   

TargetBeta-secretase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50493647(CHEMBL2437436)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coli BL21(DE3) using Biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 1 hr by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed