BDBM50495727 CHEMBL3113940
SMILES [O-][n+]1cc(Cl)c(C[C@H](OC(=O)c2ccc(cc2)C(F)(F)F)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1
InChI Key InChIKey=MESOMSSOOSHAJX-QFIPXVFZSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50495727
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Chiesi Farmaceutici
Curated by ChEMBL
Chiesi Farmaceutici
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair