BDBM50497431 CHEMBL3343672

SMILES [#7]\[#6](-[#7])=[#7]\[#6](=O)-c1ccc2-c3ccccc3[C@@]3([#6]-[#6]-[#6]-[#8]3)c2c1

InChI Key InChIKey=AWJQWLYQYNSCDJ-SFHVURJKSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50497431   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497431(CHEMBL3343672)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497431(CHEMBL3343672)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497431(CHEMBL3343672)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as [3H]PI metabolismMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50497431(CHEMBL3343672)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in CHO cells assessed as cAMP production by EIA systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed