BDBM50499194 CHEMBL3734854

SMILES OC[C@H]1CC[C@H](CC1)n1c(NC(=O)c2cccc(c2)[N+]([O-])=O)nc2cc(CN3CCCCC3)ccc12

InChI Key InChIKey=QPKFIZDVDMZSPR-IQGASKDCSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499194   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499194(CHEMBL3734854)
Affinity DataKi:  0.700nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499194(CHEMBL3734854)
Affinity DataKi:  30nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499194(CHEMBL3734854)
Affinity DataKi:  48nMAssay Description:Inhibition of IRAK-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed