BDBM50503158 CHEMBL4589377
SMILES FC(F)(F)c1c(ccn2c(CC3CC3)nnc12)-c1ccc(CNC(=O)c2ccc(cc2)S(F)(=O)=O)cc1
InChI Key InChIKey=ALLKYFRFVNIHGD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50503158
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]JNJ-46281222 from human mGlu2 receptor expressed in CHOK1 cell membranes preincubated for 3 hrs followed by [3H]JNJ-46281222 addi...More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]JNJ-46281222 from human mGlu2 receptor expressed in CHOK1 cell membranes after 1 hr by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHOK1 cell membranes assessed as increase in glutamate-induced [35S]GTPgammaS bin...More data for this Ligand-Target Pair