BDBM50504368 CHEMBL4435573

SMILES [H][C@@]12CC[C@@]3(C)C[C@@]1(C\C3=N/OCC1(C)COC1)CC[C@]1([H])[C@@](C)(CCC[C@@]21C)C(=O)OCC

InChI Key InChIKey=MKKNODUCOLIUJT-DPZKWCDVSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50504368   

TargetCoagulation factor X(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50504368(CHEMBL4435573)
Affinity DataKi:  28nMAssay Description:Inhibition of human activated Factor X using S-2765 as substrate incubated for 15 mins followed by substrate addition and measured after 1 hr by chro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50504368(CHEMBL4435573)
Affinity DataKi:  277nMAssay Description:Inhibition of human kallikrein using spectrozyme F IXa as substrate incubated for 15 mins followed by substrate addition and measured after 1 hr by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50504368(CHEMBL4435573)
Affinity DataKi:  331nMAssay Description:Inhibition of human trypsin using S-2222 as substrate incubated for 15 mins followed by substrate addition and measured after 1 hr by chromogenic ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50504368(CHEMBL4435573)
Affinity DataKi:  1.94E+3nMAssay Description:Inhibition of human activated Factor XI using S-2366 as substrate incubated for 15 mins followed by substrate addition and measured after 1 hr by chr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50504368(CHEMBL4435573)
Affinity DataKi:  2.03E+3nMAssay Description:Inhibition of human uPA using S-2586 as spectrozyme uPA substrate incubated for 15 mins followed by substrate addition and measured after 1 hr by chr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50504368(CHEMBL4435573)
Affinity DataKi:  2.83E+3nMAssay Description:Inhibition of human tPA using S-2586 as spectrozyme tPA substrate incubated for 15 mins followed by substrate addition and measured after 1 hr by chr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50504368(CHEMBL4435573)
Affinity DataKi:  4.76E+3nMAssay Description:Inhibition of human activated Factor IX using spectrozyme F IXa as substrate incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50504368(CHEMBL4435573)
Affinity DataKi:  7.64E+3nMAssay Description:Inhibition of human activated Factor XII using spectrozyme F XIIa as substrate incubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50504368(CHEMBL4435573)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of human activated Factor VII using S-2288 as substrate incubated for 15 mins followed by substrate addition and measured after 1 hr by ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B2(Homo sapiens)
Peking University

Curated by ChEMBL
LigandPNGBDBM50504368(CHEMBL4435573)
Affinity DataKi:  1.24E+4nMAssay Description:Inhibition of human chymotrypsin using S-2586 as substrate incubated for 15 mins followed by substrate addition and measured after 1 hr by chromogeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed