BDBM50507424 CHEMBL4452138

SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2nc(cs2)C(F)(F)F)c1=O

InChI Key InChIKey=YSXVOIJEAUPIBJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507424   

TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50507424(CHEMBL4452138)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50507424(CHEMBL4452138)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50507424(CHEMBL4452138)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed