BDBM50515527 CHEMBL4451049
SMILES COc1ccccc1C(N(C1CCCCC1)C(=O)\C=C\C(=O)c1ccc(C)cc1)C(=O)NC1CCCCC1
InChI Key InChIKey=GAIRAQHWWXYQQO-QURGRASLSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50515527
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade
Curated by ChEMBL
University Of Belgrade
Curated by ChEMBL
Affinity DataIC50: 5.12E+4nMAssay Description:Inhibition of TrxR in human SH-SY5Y cells using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by...More data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University Of Belgrade
Curated by ChEMBL
University Of Belgrade
Curated by ChEMBL
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of rat TrxR1 using DTNB as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
University Of Belgrade
Curated by ChEMBL
University Of Belgrade
Curated by ChEMBL
Affinity DataIC50: 5.28E+3nMAssay Description:Inhibition of TrxR1 (unknown origin) using DTNB as substrate preincubated for 30 mins in presence of insulin followed by substrate addition by colori...More data for this Ligand-Target Pair