BDBM50520828 CHEMBL4575647
SMILES COc1cc(NCCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2cccnc12
InChI Key InChIKey=MATQRKXWDVRHDA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50520828
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi Shuangliang Biotechnology
Curated by ChEMBL
Wuxi Shuangliang Biotechnology
Curated by ChEMBL
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (696-end residues) expressed in baculovirus expression system using Srctide as substrate b...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi Shuangliang Biotechnology
Curated by ChEMBL
Wuxi Shuangliang Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant expressed in baculovirus expression system by fluorescence assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuxi Shuangliang Biotechnology
Curated by ChEMBL
Wuxi Shuangliang Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant (696-end residues) by fluorescence assayMore data for this Ligand-Target Pair