BDBM50522395 CHEMBL4553424

SMILES C[C@]1(OC[C@@H](COc2ccc(cc2)N2CCN(CC2)c2ccc(NC(=O)c3ccc4ccccc4c3)cc2)O1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=XAJSCYUOMNHTBK-MMEOBGCCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50522395   

TargetSmoothened homolog(Mus musculus)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522395(CHEMBL4553424)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed