BDBM50523597 CHEMBL4561313

SMILES OC(=O)C[C@H]1CC[C@H](CC1)Oc1ccc(cn1)-c1ccc(cn1)-c1nc2cc(ccc2[nH]1)C#N

InChI Key InChIKey=ZSOYHMGKJFRGOK-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50523597   

TargetAdenosine receptor A2a(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523597(CHEMBL4561313)
Affinity DataIC50: 430nMAssay Description:Activity against human A2AR assessed as inhibition of cAMP accumulation by cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50523597(CHEMBL4561313)
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523597(CHEMBL4561313)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523597(CHEMBL4561313)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523597(CHEMBL4561313)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed