BDBM50523618 CHEMBL4527223

SMILES OC(=O)C1(COc2ccc(cn2)-c2ccc(cn2)-c2nc3cc(Cl)ccc3[nH]2)COC1

InChI Key InChIKey=RFDLYPKRPJDMDM-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50523618   

TargetSterol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523618(CHEMBL4527223)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50523618(CHEMBL4527223)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50523618(CHEMBL4527223)
Affinity DataIC50: 36nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523618(CHEMBL4527223)
Affinity DataKi:  6.54E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed