BDBM50528815 CHEMBL4468670

SMILES CCc1cnn2c(Nc3cccc(NC(=O)C=C)c3)cc(nc12)N1CCCC[C@H]1CCO

InChI Key InChIKey=CDCHESFKYUNJPV-FQEVSTJZSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50528815   

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL

LigandBDBM50528815(CHEMBL4468670)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:Competitive irreversible inhibition of CDK9/cyclin T (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL

LigandBDBM50528815(CHEMBL4468670)Copy SMILESCopy InChI

Affinity DataIC50:  932nMAssay Description:Competitive irreversible inhibition of CDK2/cyclin E (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL

LigandBDBM50528815(CHEMBL4468670)Copy SMILESCopy InChI

Affinity DataIC50:  1.20E+3nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI