BDBM50529610 CHEMBL4519857
SMILES [H][C@]12CN(c3ccnc(Nc4ccc(cc4)C(=O)NCC)n3)[C@]([H])(CN1C(=O)CC#N)C2
InChI Key InChIKey=YUJXKTRZTBIDCL-IRXDYDNUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50529610
Affinity DataIC50: 366nMAssay Description:Inhibition of human JAK2 using fluorescence labeled peptide as substrate and using ATP at its Km level by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >4.95E+3nMAssay Description:Inhibition of human JAK3 using fluorescence labeled peptide as substrate and using ATP at its Km level by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of human JAK1 using fluorescence labeled peptide as substrate and using 1 mM ATP by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 358nMAssay Description:Inhibition of human JAK1 using fluorescence labeled peptide as substrate and using ATP at its Km level by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >9.97E+3nMAssay Description:Inhibition of human JAK2 using fluorescence labeled peptide as substrate and using 1 mM ATP by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 358nMAssay Description:Inhibition of human JAK1 using fluorescence labeled peptide as substrate and using ATP at its Km level by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 366nMAssay Description:Inhibition of human JAK2 using fluorescence labeled peptide as substrate and using ATP at its Km level by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 774nMAssay Description:Inhibition of human TYK2 using fluorescence labeled peptide as substrate and using 1 mM ATP level by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human JAK3 using fluorescence labeled peptide as substrate and using 1 mM ATP by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >9.97E+3nMAssay Description:Inhibition of human JAK2 using fluorescence labeled peptide as substrate and using 1 mM ATP by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human JAK3 using fluorescence labeled peptide as substrate and using 1 mM ATP by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human TYK2 using fluorescence labeled peptide as substrate and using ATP at its Km level by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of human JAK1 using fluorescence labeled peptide as substrate and using 1 mM ATP by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human TYK2 using fluorescence labeled peptide as substrate and using ATP at its Km level by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >4.95E+3nMAssay Description:Inhibition of human JAK3 using fluorescence labeled peptide as substrate and using ATP at its Km level by microfluidic based mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 774nMAssay Description:Inhibition of human TYK2 using fluorescence labeled peptide as substrate and using 1 mM ATP level by microfluidic based mobility shift assayMore data for this Ligand-Target Pair