BDBM50530446 CHEMBL4539839

SMILES C[C@@H]1N(Cc2ccc(cc2)N=[N+]=[N-])C(=O)N(C1=O)c1ccc(Cl)cc1

InChI Key InChIKey=KEXXCOSVBSDBQV-NSHDSACASA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50530446   

TargetSmoothened homolog(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50530446(CHEMBL4539839)
Affinity DataKi:  45nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50530446(CHEMBL4539839)
Affinity DataKi:  45nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50530446(CHEMBL4539839)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at SMO in mouse NIH/3T3 cells harboring Gli-responsive firefly luciferase gene assessed as inhibition of SAG-induced response pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50530446(CHEMBL4539839)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at SMO in mouse NIH/3T3 cells harboring Gli-responsive firefly luciferase gene assessed as inhibition of SAG-induced response pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed