BDBM50534293 CHEMBL3341966

SMILES [H][C@@]12C[C@@]([H])(CNC1)c1cc(ccc21)C(F)(F)F

InChI Key InChIKey=RNOBTWYQAWEZHH-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50534293   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50534293(CHEMBL3341966)
Affinity DataIC50: 260nMAssay Description:Partial agonist activity at alpha3beta4 nAChR in HEK293 cells assessed as reduction in Ca+2 influx by FLIPR assyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50534293(CHEMBL3341966)
Affinity DataIC50: 110nMAssay Description:Partial agonist activity at alpha4beta2 nAChR in HEK293 cells assessed as reduction in Ca+2 influx by FLIPR assyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50534293(CHEMBL3341966)
Affinity DataKi:  21nMAssay Description:Displacement of [3H] epibatidine from alpha3beta4 nAChR in HEK293 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50534293(CHEMBL3341966)
Affinity DataKi:  21nMAssay Description:Displacement of [3H] epibatidine from alpha4beta2 nAChR in HEK293 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed