BDBM50534425 CHEMBL4541225

SMILES COC(=O)C1=C(CN2CC(F)(F)C[C@H]2C(O)=O)NC(=N[C@@]1(C)c1ccc(F)cc1)c1nccs1

InChI Key InChIKey=ZUNJWALIUFZGCH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50534425   

TargetCytochrome P450 2C19(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50534425(CHEMBL4541225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using substrate preincubated for 10 mins followed by NADPH addition measured after 30 mins by LC-MS/M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50534425(CHEMBL4541225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using substrate preincubated for 10 mins followed by NADPH addition measured after 30 mins by LC-MS/MS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50534425(CHEMBL4541225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using substrate preincubated for 10 mins followed by NADPH addition measured after 30 mins by LC-MS/MS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50534425(CHEMBL4541225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using substrate preincubated for 10 mins followed by NADPH addition measured after 30 mins by LC-MS/MS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50534425(CHEMBL4541225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using substrate preincubated for 10 mins followed by NADPH addition measured after 30 mins by LC-MS/MS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed