BDBM50542080 CHEMBL4649390

SMILES OC(=O)C12CCC(CC(=O)N3CCc4c(C3)n(Cc3ccc(F)cc3)c3ncccc43)(CC1)C2

InChI Key InChIKey=SGSFONPFVRRJLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542080   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542080(CHEMBL4649390)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50542080(CHEMBL4649390)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed