BDBM50546126 CHEMBL4741014
SMILES N[C@H]([C@@H](O)CN(C1COC1)S(=O)(=O)c1ccc(Cl)c(Cl)c1)c1ccccc1
InChI Key InChIKey=DOGJGYGQVXVFTC-ROUUACIJSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50546126
TargetPresenilin-1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in HEK293 cells cotransfected with Notch1-VP16-GAL4 fusion and Gal4 luciferase reporter plas...More data for this Ligand-Target Pair
TargetSignal peptide peptidase-like 2A(Homo sapiens)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human SPPL2a expressed in HEK293 cells cotransfected with Gal4 luciferase reporter plasmid and VP16-TNFalpha(1-76)-NTF incubated for 24...More data for this Ligand-Target Pair