BDBM50553944 CHEMBL4780624
SMILES CCOC(=O)[C@@H](Cc1ncccn1)NC(=O)Nc1c2CCCc2cc2CCCc12
InChI Key InChIKey=DGKQGJVFBMUMLC-GOSISDBHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50553944
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera
Curated by ChEMBL
Nodthera
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera
Curated by ChEMBL
Nodthera
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as reduction in nigercin-induced ASC speck formation measuring green fluorescent protein aggregatio...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Nodthera
Curated by ChEMBL
Nodthera
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of NLRP3 in human whole blood assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair