BDBM50556445 CHEMBL4753762

SMILES NC(=O)c1cc(ccc1O)C(=O)c1sc(NC(=O)C2(CC2)c2ccc3OCOc3c2)nc1-c1ccccc1

InChI Key InChIKey=YSEZLMSVNXMQBI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50556445   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50556445(CHEMBL4753762)
Affinity DataEC50:  1.37E+4nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed