BDBM50559543 CHEMBL4754086
SMILES Cn1cc2cc(ccc2n1)-n1nc2ccc(OCC(F)F)nc2c(-c2ccc(OC(F)F)cc2)c1=O
InChI Key InChIKey=INTOGIZNZMXCPU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50559543
Affinity DataIC50: <100nMAssay Description:Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s...More data for this Ligand-Target Pair