BDBM50559544 CHEMBL4751206

SMILES COc1ccc(cn1)-c1c2nc(OCC(F)F)ccc2nn(-c2ccc3nn(C)cc3c2)c1=O

InChI Key InChIKey=ALFMCTOWHKIARN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559544   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50559544(CHEMBL4751206)
Affinity DataIC50: <100nMAssay Description:Inhibition of MAT2A in human HCT-116 cells assessed as reduction in SAM incubated for 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50559544(CHEMBL4751206)
Affinity DataIC50: <100nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells using L-methionine as substrate incubated for 60 mins followed by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed