BDBM50563993 CHEMBL4792403

SMILES [#6]-[#7](-[#6]-[#6]\[#6]=[#6](\c1sccc1-[#6])-c1sccc1-[#6])-[#6](-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]-c1ccccc1

InChI Key InChIKey=KFCRYPYOVFYCOT-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50563993   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50563993(CHEMBL4792403)
Affinity DataKi:  2.45E+4nMAssay Description:Displacement of [3H]NO711 from mouse GAT1 expressed in HEK293 cells measured after 40 mins of incubation by LC-ESI-MS-MS methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50563993(CHEMBL4792403)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50563993(CHEMBL4792403)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50563993(CHEMBL4792403)
Affinity DataIC50:  6.61E+3nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50563993(CHEMBL4792403)
Affinity DataIC50:  6.31E+3nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed