BDBM50566470 CHEMBL4857523

SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](O)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)C(O)=O)C(O)=O

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50566470   

TargetGlucagon receptor(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566470(CHEMBL4857523)
Affinity DataIC50:  0.430nMAssay Description:Antagonist activity at human GCGR expressed in HEK293 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566470(CHEMBL4857523)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at human GIPR expressed in HEK293 cells assessed as inhibition of GIP-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Mus musculus)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566470(CHEMBL4857523)
Affinity DataIC50:  131nMAssay Description:Antagonist activity at mouse GLP1R expressed in CHO-K1 cells assessed as inhibition of GLP1-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Mus musculus)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566470(CHEMBL4857523)
Affinity DataIC50:  0.530nMAssay Description:Antagonist activity at mouse GCGR expressed in CHO-K1 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Mus musculus)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566470(CHEMBL4857523)
Affinity DataIC50:  125nMAssay Description:Antagonist activity at mouse GIPR expressed in CHO-K1 cells assessed as inhibition of GIP-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566470(CHEMBL4857523)
Affinity DataIC50:  99nMAssay Description:Antagonist activity at human GLP-1R expressed in HEK293 cells assessed as inhibition of GLP1-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed