BDBM50569446 CHEMBL4870406

SMILES Clc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)C(=O)Nc1ccc(OCCCCc2ccccc2)cc1

InChI Key InChIKey=AVJDXAXTOWGORX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50569446   

TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569446(CHEMBL4870406)
Affinity DataIC50: 240nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGE2 production incubated for 24 hrs by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569446(CHEMBL4870406)
Affinity DataIC50: 490nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 cells microsomes assessed as reduction in PGE2 production preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569446(CHEMBL4870406)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in IL-1beta stimulated PGI2 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50569446(CHEMBL4870406)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed