BDBM50570959 CHEMBL4870780

SMILES CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@H](O)c2cccc(C)c2)cc1C

InChI Key InChIKey=GZISLAWEFNWGCT-JOCHJYFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570959   

TargetEukaryotic translation initiation factor 2 subunit 1(Homo sapiens)
Hibercell

Curated by ChEMBL
LigandPNGBDBM50570959(CHEMBL4870780)
Affinity DataIC50:  54nMAssay Description:Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Hibercell

Curated by ChEMBL
LigandPNGBDBM50570959(CHEMBL4870780)
Affinity DataIC50:  3nMAssay Description:Inhibition of human His-tagged PERK expressed in Escherichia coli assessed as eIF2alpha phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed