BDBM50571456 CHEMBL4851518
SMILES O=c1cc(cc([nH]1)N1CCC[C@H]1Cc1ccccc1)N1CCOCC1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50571456
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River
Curated by ChEMBL
Charles River
Curated by ChEMBL
Affinity DataKi: 630nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Affinity DataKi: >900nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair