BDBM50571465 CHEMBL4852165
SMILES Oc1cc(nc(n1)N1CCOCC1)N1CCC[C@@H]1Cc1ccccc1
InChI Key InChIKey=BZDFDZUZTQDDOL-MRXNPFEDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50571465
Affinity DataKi: 87nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River
Curated by ChEMBL
Charles River
Curated by ChEMBL
Affinity DataKi: 270nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair