BDBM50572647 CHEMBL4855001

SMILES Cc1ccc(CN2CCN(CC2)C(=O)C(=O)Nc2ccc3n(C)cc(F)c3c2)cc1

InChI Key InChIKey=YBNNEUVNSBOAPO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50572647   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50572647(CHEMBL4855001)
Affinity DataEC50:  85nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in Flp-In-HEK293 cells co-expressing RIC-3 assessed as potentiation of PNU2829...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed