BDBM50573140 CHEMBL4862672

SMILES CN(C)C(=O)c1cnc2ccc(CN(C)c3nnc(o3)-c3ccc(cc3C)-c3c(C)nn(C)c3C)cn12

InChI Key InChIKey=FOXUEUUXDNQMCT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50573140   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573140(CHEMBL4862672)
Affinity DataIC50:  32nMAssay Description:Inhibition of FLAG-tagged MER (unknown origin) transfected in Cos-7cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573140(CHEMBL4862672)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of FLAG-tagged Tyro3 (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573140(CHEMBL4862672)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of FLAG-tagged FLT3 (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573140(CHEMBL4862672)
Affinity DataIC50:  398nMAssay Description:Inhibition of FLAG-tagged AXL (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed