BDBM50576221 CHEMBL4848404

SMILES CC(COc1ccc2c(C)c(CN3CC4(CCN(CC4)c4nccn5ccnc45)NC3=O)c(=O)oc2c1)c1ccccc1

InChI Key InChIKey=DXZIFYLQKRVPBF-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50576221   

TargetImmunoglobulin lambda variable 6-57(Homo sapiens)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50576221(CHEMBL4848404)
Affinity DataEC50:  187nMAssay Description:Stabilization of AL patient derived fluorescein-labeled IGLV6-57 T46L/F49Y mutant measured after 24 hrs by proteolysis coupled-fluorescence polarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetImmunoglobulin lambda variable 6-57(Homo sapiens)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50576221(CHEMBL4848404)
Affinity DataEC50:  299nMAssay Description:Stabilization of AL patient derived full length fluorescein-labeled IGLV6-57 expressed in Escherichia coli BL21 (DE3) measured after 24 hrs by proteo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetImmunoglobulin lambda variable 6-57(Homo sapiens)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50576221(CHEMBL4848404)
Affinity DataEC50:  299nMAssay Description:Stabilization of AL patient derived full length fluorescein-labeled IGLV6-57 expressed in Escherichia coli BL21 (DE3) measured after 24 hrs by proteo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetImmunoglobulin lambda variable 6-57(Homo sapiens)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50576221(CHEMBL4848404)
Affinity DataEC50:  187nMAssay Description:Stabilization of AL patient derived fluorescein-labeled IGLV6-57 T46L/F49Y mutant measured after 24 hrs by proteolysis coupled-fluorescence polarizat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed