BDBM50576221 CHEMBL4848404
SMILES CC(COc1ccc2c(C)c(CN3CC4(CCN(CC4)c4nccn5ccnc45)NC3=O)c(=O)oc2c1)c1ccccc1
InChI Key InChIKey=DXZIFYLQKRVPBF-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50576221
TargetImmunoglobulin lambda variable 6-57(Homo sapiens)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataEC50: 187nMAssay Description:Stabilization of AL patient derived fluorescein-labeled IGLV6-57 T46L/F49Y mutant measured after 24 hrs by proteolysis coupled-fluorescence polarizat...More data for this Ligand-Target Pair
TargetImmunoglobulin lambda variable 6-57(Homo sapiens)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataEC50: 299nMAssay Description:Stabilization of AL patient derived full length fluorescein-labeled IGLV6-57 expressed in Escherichia coli BL21 (DE3) measured after 24 hrs by proteo...More data for this Ligand-Target Pair
TargetImmunoglobulin lambda variable 6-57(Homo sapiens)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataEC50: 299nMAssay Description:Stabilization of AL patient derived full length fluorescein-labeled IGLV6-57 expressed in Escherichia coli BL21 (DE3) measured after 24 hrs by proteo...More data for this Ligand-Target Pair
TargetImmunoglobulin lambda variable 6-57(Homo sapiens)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataEC50: 187nMAssay Description:Stabilization of AL patient derived fluorescein-labeled IGLV6-57 T46L/F49Y mutant measured after 24 hrs by proteolysis coupled-fluorescence polarizat...More data for this Ligand-Target Pair