BDBM50578339 CHEMBL4875081

SMILES COc1ccc(Cl)cc1[C@H]1C[C@@H]1CNCCCOc1ccc2ccc(=O)[nH]c2c1

InChI Key

Data  13 KI  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50578339   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-N-methylspiperone from D2 receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scinti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-N-methylspiperone from D2 receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scinti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-LSD from 5HT1A receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-LSD from 5HT1A receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-SCH23390 from D3 receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-SCH23390 from D3 receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  603nMAssay Description:Displacement of [3H]-SCH23390 from D4 receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  603nMAssay Description:Displacement of [3H]-LSD from 5HT2C receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  604nMAssay Description:Displacement of [3H]-SCH23390 from D4 receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  604nMAssay Description:Displacement of [3H]-LSD from 5HT2C receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]-LSD from 5HT2A receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi:  1.16E+3nMAssay Description:Displacement of [3H]-LSD from 5HT2A receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-SCH23390 from D1 receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  8.30nMAssay Description:Partial agonist activity at D2 receptor (unknown origin) expressed in HEK293T cells co-expressing GFP2-beta-arrestin2 assessed as beta-arrestin2 recr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  3.40nMAssay Description:Partial agonist activity at D2 receptor (unknown origin) expressed in HEK293T cells co-expressing Rluc8-tagged Galpahi1 assessed as Galphai1 dissocia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  3.40nMAssay Description:Partial agonist activity at D2 receptor (unknown origin) expressed in HEK293T cells co-expressing Rluc8-tagged Galpahi1 assessed as Galphai1 dissocia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  2nMAssay Description:Partial agonist activity at D2 receptor (unknown origin) expressed in HEK293T cells co-expressing GalphaoA preincubated for 2 mins with coelenterazin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  129nMAssay Description:Partial agonist activity at D3 receptor (unknown origin) expressed in HEK293T cells co-expressing GalphaoA preincubated for 2 mins with coelenterazin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  129nMAssay Description:Partial agonist activity at D3 receptor (unknown origin) expressed in HEK293T cells co-expressing GalphaoA preincubated for 2 mins with coelenterazin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  13nMAssay Description:Partial agonist activity at D3 receptor (unknown origin) expressed in HEK293T cells co-expressing GFP2-beta-arrestin2 assessed as beta-arrestin2 recr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  13nMAssay Description:Partial agonist activity at D3 receptor (unknown origin) expressed in HEK293T cells co-expressing GFP2-beta-arrestin2 assessed as beta-arrestin2 recr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  59nMAssay Description:Partial agonist activity at 5HT1A receptor (unknown origin) expressed in HEK293T cells co-expressing Rluc8-tagged Galpahi1 preincubated for 2 mins wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  8.30nMAssay Description:Partial agonist activity at D2 receptor (unknown origin) expressed in HEK293T cells co-expressing GFP2-beta-arrestin2 assessed as beta-arrestin2 recr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  59nMAssay Description:Partial agonist activity at 5HT1A receptor (unknown origin) expressed in HEK293T cells co-expressing Rluc8-tagged Galpahi1 preincubated for 2 mins wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50578339(CHEMBL4875081)
Affinity DataEC50:  2nMAssay Description:Partial agonist activity at D2 receptor (unknown origin) expressed in HEK293T cells co-expressing GalphaoA preincubated for 2 mins with coelenterazin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed