BDBM50579519 CHEMBL3912712

SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(O)=N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F

InChI Key

Data  8 IC50

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50579519   

LigandPNGBDBM50579519(CHEMBL3912712)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(O)=N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM50579519(CHEMBL3912712)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(O)=N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM50579519(CHEMBL3912712)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(O)=N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Affinity DataIC50: 10nMAssay Description:Inhibition of rat recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCMS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetStanniocalcin-1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50579519(CHEMBL3912712)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(O)=N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Affinity DataIC50: 88nMAssay Description:Inhibition of mouse STC1 in cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetAcyl-CoA wax alcohol acyltransferase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50579519(CHEMBL3912712)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(O)=N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human AWAT2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50579519(CHEMBL3912712)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(O)=N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetStanniocalcin-1(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM50579519(CHEMBL3912712)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(O)=N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Affinity DataIC50: 33nMAssay Description:Inhibition of human STC1 in cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM50579519(CHEMBL3912712)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(O)=N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Affinity DataIC50: 820nMAssay Description:Inhibition of human MGAT3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid