BDBM50582730 CHEMBL5087055

SMILES Cc1c(cnn1[C@@H]2CCOC2)Nc3nc(c4c(c(n(c4n3)C)N5CCC[C@H]5C)C#N)N

InChI Key InChIKey=QSDVZPULRUJSBC-UHFFFAOYSA-N

Data  8 IC50  4 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50582730   

TargetMitogen-activated protein kinase kinase kinase 1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582730BDBM50582730(CHEMBL5087055)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MAP3K1 expressed in human PBMCs measured by KiNativ profiling analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed