BDBM50583744 CHEMBL5082456

SMILES CCCCn1c(C)nc2ccc(nc12)-c1cc(N)nc(N)c1

InChI Key InChIKey=NTTSIVMHWLTUFK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50583744   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50583744(CHEMBL5082456)
Affinity DataIC50:  2nMAssay Description:Inhibition of DYRK1A (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50583744(CHEMBL5082456)
Affinity DataIC50:  100nMAssay Description:Inhibition of wild type full length DYRK1A (unknown origin) in human U2OS cells assessed as reduction in pSER520 autophosphorylation incubated for 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50583744(CHEMBL5082456)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed