BDBM50583928 CHEMBL5080711

SMILES CC1(C)CNC[C@H](C1)Nc1ncc(c(n1)-c1c[nH]c2c(c(ccc12)C#N)P(C)(C)=O)C(F)(F)F

InChI Key InChIKey=DQFXKZPDQHUJLY-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50583928   

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Syros Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583928BDBM50583928(CHEMBL5080711)
Affinity DataKd:  0.0600nMAssay Description:Binding affinity to full length CDK7 (1 to 346 residues) /N-terminal TEV cleavable 6His tagged full length cyclinH (1 to 323 residues) (unknown origi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed