BDBM50594731 CHEMBL1241028

SMILES Clc1c2C(=O)CC(=O)c2c(Cl)c(Cl)c1Cl

InChI Key InChIKey=IDLAOWFFKWRNHB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594731   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50594731(CHEMBL1241028)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant human UCHL3 expressed in baculovirus infected Sf9 cells using ubiquitin-AMC as substrate preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50594731(CHEMBL1241028)
Affinity DataIC50:  1.84E+3nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReplicase polyprotein 1ab(2019-nCoV)
University of Colorado

Curated by ChEMBL
LigandPNGBDBM50594731(CHEMBL1241028)
Affinity DataIC50:  1.38E+5nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli using DABCYL-KTSAVLQ1SGFRKM-E(EDANS)-NH2 peptide as substrate incubated for 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed