BDBM50609669 CHEMBL5288393

SMILES CCCOc1ccc(NC(=O)C(C)(C)c2csc(NS(=O)(=O)C3CC3)n2)cc1

InChI Key InChIKey=BOEWQRNBSGZWMC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50609669   

TargetCTP synthase 1(Homo sapiens)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609669(CHEMBL5288393)
Affinity DataIC50:  3.83E+5nMAssay Description:Inhibition of C-terminal FLAG-His8-tagged full length human CTPS1 preincubated for 10 mins followed by substrate addition by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCTP synthase 1(Mus musculus)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609669(CHEMBL5288393)
Affinity DataIC50:  440nMAssay Description:Inhibition of mouse CTPS1 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCTP synthase 1(Homo sapiens)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50609669(CHEMBL5288393)
Affinity DataIC50:  580nMAssay Description:Inhibition of human CTPS1 preincubated for 10 mins followed by substrate addition and measured after 30 to 60 mins by RFMS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed