BDBM50614138 CHEMBL5283494

SMILES O=C1CC2CCc3ccsc3C2=NN1CCN1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=BNGICRROXYSOFL-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50614138   

TargetCholinesterase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614138(CHEMBL5283494)
Affinity DataIC50: 5.11E+3nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614138(CHEMBL5283494)
Affinity DataIC50: 170nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAcetylcholinesterase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614138(CHEMBL5283494)
Affinity DataKi:  123nMAssay Description:Competitive inhibition of human AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by varing concentratio...More data for this Ligand-Target Pair
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614138(CHEMBL5283494)
Affinity DataKi:  1.08E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK cell membrane incubated for 120 mins by microplate beta scintillation coun...More data for this Ligand-Target Pair
In DepthDetails
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50614138(CHEMBL5283494)
Affinity DataKi:  1.67E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK cell membrane incubated for 60 mins by microplate beta scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails
PubMed