BDBM507023 US11046671, VTX-133

SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)-c1cccnc1

InChI Key InChIKey=PBBAJCCCVCCZPV-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507023   

TargetToll-like receptor 8(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM507023(US11046671, VTX-133)
Affinity DataEC50:  77nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent