BDBM507047 2-Amino-8-(6-chloro-1,4-dihydroquinazolin-2-yl)-N,N-dipropyl-3H-1-benzazepine-4-carboxamide::US11046671, Example 8

SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C1=NCc2cc(C)ccc2N1

InChI Key InChIKey=LXOUICLSXDFWTO-UHFFFAOYSA-N

Data  2 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 507047   

TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche Inc.

US Patent
LigandPNGBDBM507047(2-Amino-8-(6-chloro-1,4-dihydroquinazolin-2-yl)-N,...)
Show SMILES CCCN(CCC)C(=O)C1=Cc2ccc(cc2N=C(N)C1)C1=NCc2cc(C)ccc2N1
Show InChI InChI=1S/C26H31N5O/c1-4-10-31(11-5-2)26(32)20-13-18-7-8-19(14-23(18)29-24(27)15-20)25-28-16-21-12-17(3)6-9-22(21)30-25/h6-9,12-14H,4-5,10-11,15-16H2,1-3H3,(H2,27,29)(H,28,30)
Affinity DataEC50: >1.00E+5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid