BDBM509661 Methyl 3-[2-[[2-(tert-butylcarbamoyl)-4-pyridyl]amino]-2-oxo-ethyl]-4-hydroxy-benzoate::US11364246, Example 13::US20200361871A1, Example 13

SMILES COC(=O)c1ccc(O)c(CC(=O)Nc2ccnc(c2)C(=O)NC(C)(C)C)c1

InChI Key InChIKey=JYNLGWPCZOXRSQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509661   

TargetAnoctamin-1(Homo sapiens (Human))
Tmem16A

US Patent
LigandPNGBDBM509661(Methyl 3-[2-[[2-(tert-butylcarbamoyl)-4-pyridyl]am...)
Affinity DataEC50:  1.00E+3nMAssay Description:Cell Culture and PreparationFisher rat thyroid (FRT) cells stably expressing human TMEM16A (TMEM16Aabc variant; Dr Luis Galietta, Insituto Giannina, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-1(Homo sapiens (Human))
Tmem16A

US Patent
LigandPNGBDBM509661(Methyl 3-[2-[[2-(tert-butylcarbamoyl)-4-pyridyl]am...)
Affinity DataEC50:  1.00E+3nMAssay Description:Compound activity was quantified by measuring the increase in current upon compound addition and expressing this as a percentage increase of baseline...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent