BDBM535412 US11236047, Example 140::US11236047, Example 141::US20230338337, Compound 141

SMILES CCOCC(C)(O)c1cc2C(=O)N(Cc3ccc(Cl)cn3)[C@](O[C@H]3CCOC3)(c2c(F)c1)c1ccc(Cl)cc1

InChI Key InChIKey=LWOJSHCDLMMOQI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 535412   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM535412(US11236047, Example 141 | US11236047, Example 140 ...)
Affinity DataIC50: 0.700nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandPNGBDBM535412(US11236047, Example 141 | US11236047, Example 140 ...)
Affinity DataIC50: 17nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent