BDBM535425 (3R)-3-(4-chlorophenyl)-2-[(5- chloropyridin-2-yl)methyl]-4-fluoro-6- [1-hydroxy-1-(1-methyl-1H-pyrazol-4- yl)ethyl]-3-[(2R)-2-hydroxypropoxy]- 2,3-dihydro-1H-isoindol-1-one::US11236047, Example 221::US11236047, Example 354::US20230338337, Compound 354
SMILES C[C@@H](O)CO[C@]1(N(Cc2ccc(Cl)cn2)C(=O)c2cc(cc(F)c12)C(C)(O)c1cnn(C)c1)c1ccc(Cl)cc1
InChI Key InChIKey=MNQQXUGKGLDIBL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 535425
Affinity DataIC50: 33nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair