BDBM545130 US11286268, Compound 616
SMILES CN1CCN(Cc2c(cc3nc(C)n(CC#Cc4ccc(Cl)cc4-c4cc(C)nc5c(csc45)C(O)=O)c(=O)c3c2C#N)C(F)(F)F)CC1
InChI Key InChIKey=OWUIRLUOYKZEHF-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 545130
TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
Effector Therapeutics
US Patent
Effector Therapeutics
US Patent
Affinity DataIC50: 2.45nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair