BDBM545212 US11286268, Compound 698

SMILES Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cc(Cl)c(N4CC(O)C4)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

InChI Key InChIKey=RIGRWJBAHFVYFL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 545212   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
Effector Therapeutics

US Patent
LigandPNGBDBM545212(US11286268, Compound 698)
Affinity DataIC50:  3.40nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent