BDBM545293 US11286268, Compound 781

SMILES CN(C)C(=O)c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

InChI Key InChIKey=QGIBKNRSIIKYAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 545293   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
Effector Therapeutics

US Patent
LigandPNGBDBM545293(US11286268, Compound 781)
Affinity DataIC50:  3.12nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent