BDBM545305 US11286268, Compound 792

SMILES Cc1cc(-c2cc(Cl)ccc2OCCn2c(C)nc3cnc(Cl)c(C#N)c3c2=O)c2scc(C(O)=O)c2n1

InChI Key InChIKey=XSGSXPXUPVXDEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 545305   

TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
Effector Therapeutics

US Patent
LigandPNGBDBM545305(US11286268, Compound 792)
Affinity DataIC50:  2.44nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent