BDBM546106 US11286268, Compound 1605
SMILES CN(C1CCN(CC(C)(F)F)CC1)c1ncc2nc(C)n(CC#Cc3ccc(Cl)cc3-c3ccnc4c(csc34)C(=O)NS(=O)(=O)C(C)(C)C)c(=O)c2c1C#N
InChI Key InChIKey=WYAALRGMSGIFBQ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 546106
TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
Effector Therapeutics
US Patent
Effector Therapeutics
US Patent
Affinity DataIC50: 3.78nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair